A1C, Sickle Cell Trait And Other Hemoglobin Variants

The a1c test is used to monitor the glucose levels of patients who have been diagnosed with diabetes. in people who have hemoglobin variants such as hbs (sickle cell trait), some a1c tests give falsely high or low readings that can lead to the over-treatment or under-treatment of diabetes.. A1c test. the a1c test is sometimes called the hemoglobin a1c, hba1c, glycated hemoglobin, or glycohemoglobin test. uses. screening and diagnosis of prediabetes 1. 5.7–6.4% 1; screening and diagnosis of type 2 diabetes 1. 6.5% or higher 1; repeat for confirmation of diagnosis. Sickle cell trait and other hemoglobinopathies and diabetes (for providers) explains how the a1c test can lead to misdiagnosis, overtreatment, or undertreatment of diabetes in people with hemoglobinopathies. explains when to suspect a patient has a variant..

The a1c test, also known as an hba1c, hemoglobin a1c, glycated hemoglobin, or glycosylated hemoglobin test, is a blood test that shows your average blood sugar levels for the past two to three months.it’s a broader test than conventional home glucose monitoring, which measures your blood sugar at any given moment.it’s used to diagnose and monitor diabetes.. Marked discrepancies between measured a1c and plasma glucose levels should prompt consideration that the a1c assay may not be reliable for that individual. for patients with a hemoglobin variant but normal red blood cell turnover, such as those with the sickle cell trait, an a1c assay without interference from hemoglobin variants should be used..

Hemoglobin variants are a part of the normal embryonic and fetal development. they may also be pathologic mutant forms of hemoglobin in a population, caused by variations in genetics. some well-known hemoglobin variants, such as sickle-cell anemia, are responsible for diseases and are considered hemoglobinopathies.. Abnormal forms of hemoglobin – the presence of some hemoglobin variants, such as hemoglobin s in sickle cell anemia, may affect certain methods for measuring a1c. furthermore, the national institute of diabetes and digestive and kidney diseases (niddk) recommends against the use of the a1c test in patients with the hemoglobin variants hbss.

Abnormal forms of hemoglobin – the presence of some hemoglobin variants, such as hemoglobin s in sickle cell anemia, may affect certain methods for measuring a1c. furthermore, the national institute of diabetes and digestive and kidney diseases (niddk) recommends against the use of the a1c test in patients with the hemoglobin variants hbss. A1c test. the a1c test is sometimes called the hemoglobin a1c, hba1c, glycated hemoglobin, or glycohemoglobin test. uses. screening and diagnosis of prediabetes 1. 5.7–6.4% 1; screening and diagnosis of type 2 diabetes 1. 6.5% or higher 1; repeat for confirmation of diagnosis.